Expresión de búsqueda: VASCULAR ENDOTHELIAL GROWTH FACTOR A 
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Descriptor Inglés:   Vascular Endothelial Growth Factor A 
Descriptor Español:   Factor A de Crecimiento Endotelial Vascular 
Descriptor Portugués:   Fator A de Crescimento do Endotélio Vascular 
Sinónimos Inglés:   Vascular Endothelial Growth Factor
Vascular Endothelial Growth Factor-A  
Categoría:   D12.644.276.100.800.200
D12.776.467.100.800.200
D23.529.100.800.200
Definición Inglés:   The original member of the family of endothelial cell growth factors referred to as VASCULAR ENDOTHELIAL GROWTH FACTORS. Vascular endothelial growth factor-A was originally isolated from tumor cells and referred to as "tumor angiogenesis factor" and "vascular permeability factor". Although expressed at high levels in certain tumor-derived cells it is produced by a wide variety of cell types. In addition to stimulating vascular growth and vascular permeability it may play a role in stimulating VASODILATION via NITRIC OXIDE-dependent pathways. Alternative splicing of the mRNA for vascular endothelial growth factor A results in several isoforms of the protein being produced. 
Nota Histórica Inglés:   2004; use VASCULAR ENDOTHELIAL GROWTH FACTOR A (NM) 2000-2002 
Calificadores Permitidos Inglés:  
AD administration & dosage AE adverse effects
AG agonists AN analysis
AI antagonists & inhibitors BI biosynthesis
BL blood CF cerebrospinal fluid
CS chemical synthesis CH chemistry
CL classification CT contraindications
DF deficiency DU diagnostic use
DE drug effects EC economics
GE genetics HI history
IM immunology IP isolation & purification
ME metabolism PK pharmacokinetics
PD pharmacology PH physiology
PO poisoning RE radiation effects
SE secretion ST standards
SD supply & distribution TU therapeutic use
TO toxicity UL ultrastructure
UR urine  
Número del Registro:   38244 
Identificador Único:   D042461 

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